{"id":2591,"date":"2023-04-04T10:37:06","date_gmt":"2023-04-04T03:37:06","guid":{"rendered":"https:\/\/opfe.vn\/?p=2591"},"modified":"2024-01-11T11:48:34","modified_gmt":"2024-01-11T04:48:34","slug":"cu-the-ve-dac-tinh-tri-dai-thao-duong-o-nam-muc-coprinus-comatus","status":"publish","type":"post","link":"https:\/\/opfe.vn\/index.php\/2023\/04\/04\/cu-the-ve-dac-tinh-tri-dai-thao-duong-o-nam-muc-coprinus-comatus\/","title":{"rendered":"[C\u1ee4 TH\u1ec2 V\u1ec0 \u0110\u1eb6C T\u00cdNH TR\u1eca \u0110\u00c1I TH\u00c1O \u0110\u01af\u1edcNG \u1ede N\u1ea4M M\u1ef0C COPRINUS COMATUS]"},"content":{"rendered":"\n

1. B\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng l\u00e0 g\u00ec?<\/strong><\/h4>\n\n\n\n

\u0110\u00e1i th\u00e1o \u0111\u01b0\u1eddng hay c\u00f2n g\u1ecdi l\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng, l\u00e0 b\u1ec7nh r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a \u0111\u1eb7c tr\u01b0ng v\u1edbi bi\u1ec3u hi\u1ec7n l\u01b0\u1ee3ng \u0111\u01b0\u1eddng \u1edf trong m\u00e1u lu\u00f4n \u1edf m\u1ee9c cao h\u01a1n so v\u1edbi b\u00ecnh th\u01b0\u1eddng do c\u01a1 th\u1ec3 thi\u1ebfu h\u1ee5t v\u1ec1 ti\u1ebft insulin ho\u1eb7c \u0111\u1ec1 kh\u00e1ng v\u1edbi insulin ho\u1eb7c c\u1ea3 2, d\u1eabn \u0111\u1ebfn r\u1ed1i lo\u1ea1n quan tr\u1ecdng v\u1ec1 chuy\u1ec3n h\u00f3a \u0111\u01b0\u1eddng, \u0111\u1ea1m, m\u1ee1, ch\u1ea5t kho\u00e1ng.<\/p>\n\n\n\n

Khi <\/a>m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng, c\u01a1 th\u1ec3 kh\u00f4ng th\u1ec3 t\u1ef1 chuy\u1ec3n h\u00f3a c\u00e1c ch\u1ea5t b\u1ed9t \u0111\u01b0\u1eddng t\u1eeb c\u00e1c th\u1ef1c ph\u1ea9m \u0103n v\u00e0o h\u00e0ng ng\u00e0y \u0111\u1ec3 t\u1ea1o ra n\u0103ng l\u01b0\u1ee3ng, l\u00e2u d\u1ea7n g\u00e2y n\u00ean hi\u1ec7n t\u01b0\u1ee3ng t\u0103ng d\u1ea7n l\u01b0\u1ee3ng \u0111\u01b0\u1eddng t\u00edch t\u1ee5 trong m\u00e1u. N\u1ebfu l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u lu\u00f4n \u1edf m\u1ee9c cao s\u1ebd l\u00e0m gia t\u0103ng c\u00e1c nguy c\u01a1 b\u1ec7nh l\u00fd tim m\u1ea1ch, \u0111\u1ed3ng th\u1eddi g\u00e2y t\u1ed5n th\u01b0\u01a1ng \u1edf nhi\u1ec1u c\u01a1 quan b\u1ed9 ph\u1eadn kh\u00e1c nh\u01b0 th\u1ea7n kinh, m\u1eaft, th\u1eadn v\u00e0 nhi\u1ec1u b\u1ec7nh l\u00fd nghi\u00eam tr\u1ecdng kh\u00e1c.<\/p>\n\n\n\n

2. C\u00e1c lo\u1ea1i ti\u1ec3u \u0111\u01b0\u1eddng th\u01b0\u1eddng g\u1eb7p<\/strong><\/h4>\n\n\n\n

\"\ud83d\udccc\" Ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1<\/h4>\n\n\n\n

Th\u1ec3 b\u1ec7nh do t\u1ebf b\u00e0o beta c\u1ee7a tuy\u1ebfn t\u1ee5y b\u1ecb ph\u00e1 h\u1ee7y g\u00e2y gi\u1ea3m ti\u1ebft insulin ho\u1eb7c kh\u00f4ng ti\u1ebft ra insulin, khi\u1ebfn l\u01b0\u1ee3ng insulin l\u01b0u h\u00e0nh trong m\u00e1u r\u1ea5t \u00edt, kh\u00f4ng th\u1ec3 \u0111i\u1ec1u h\u00f2a l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u, g\u00e2y nguy hi\u1ec3m \u0111\u1ebfn t\u00ednh m\u1ea1ng b\u1ec7nh nh\u00e2n.<\/p>\n\n\n\n

Ph\u1ea7n l\u1edbn ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1 th\u01b0\u1eddng g\u1eb7p nh\u1ea5t l\u00e0 d\u01b0\u1edbi 20 tu\u1ed5i, chi\u1ebfm kho\u1ea3ng 5 \u2013 10% t\u1ed5ng s\u1ed1 tr\u01b0\u1eddng h\u1ee3p m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng<\/p>\n\n\n\n

\"\ud83d\udccc\" Ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 2<\/h4>\n\n\n\n

Tr\u01b0\u1edbc kia \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng c\u1ee7a ng\u01b0\u1eddi l\u1edbn tu\u1ed5i hay ti\u1ec3u \u0111\u01b0\u1eddng kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o insulin. \u1ede th\u1ec3 b\u1ec7nh n\u00e0y, insulin do tuy\u1ebfn t\u1ee5y ti\u1ebft ra m\u1eb7c d\u00f9 \u0111\u1ea1t s\u1ed1 l\u01b0\u1ee3ng nh\u01b0 ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng nh\u01b0ng l\u1ea1i gi\u1ea3m, ho\u1eb7c kh\u00f4ng c\u00f3 vai tr\u00f2 \u0111i\u1ec1u h\u00f2a l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u do gi\u1ea3m ch\u1ee9c n\u0103ng c\u1ee7a t\u1ebf b\u00e0o beta tuy\u1ebfn t\u1ee5y ti\u1ebfn tri\u1ec3n tr\u00ean n\u1ec1n t\u1ea3ng \u0111\u1ec1 kh\u00e1ng insulin.<\/p>\n\n\n\n

\u0110\u00e2y l\u00e0 th\u1ec3 b\u1ec7nh ph\u1ed5 bi\u1ebfn nh\u1ea5t, g\u1eb7p nhi\u1ec1u nh\u1ea5t \u1edf ng\u01b0\u1eddi tr\u00ean 40 tu\u1ed5i v\u00e0 c\u00f3 xu h\u01b0\u1edbng d\u1ea7n tr\u1ebb h\u00f3a. S\u1ed1 b\u1ec7nh nh\u00e2n \u1edf th\u1ec3 n\u00e0y chi\u1ebfm \u0111\u1ebfn 90 \u2013 95% t\u1ed5ng s\u1ed1 c\u00e1c tr\u01b0\u1eddng h\u1ee3p m\u1eafc b\u1ec7nh.<\/p>\n\n\n\n

\"\ud83c\udf44\" \u0110\u1eb7c t\u00ednh tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng \u1edf N\u1ea5m M\u1ef1c – Coprinus Comatus<\/strong><\/h4>\n\n\n\n

C\u00f4ng d\u1ee5ng h\u1ea1 v\u00e0 \u1ed5n \u0111\u1ecbnh \u0111\u01b0\u1eddng huy\u1ebft c\u1ee7a N\u1ea5m M\u1ef1c \u0111\u01b0\u1ee3c gi\u1edbi khoa h\u1ecdc ch\u00fa \u00fd nhi\u1ec1u nh\u1ea5t b\u1edfi c\u01a1 th\u1ec3 \u0111\u1eadu qu\u1ea3 l\u00ean men c\u1ee7a n\u00f3 r\u1ea5t gi\u00e0u Vanadium – m\u1ed9t lo\u1ea1i kho\u00e1ng ch\u1ea5t qu\u00fd hi\u1ebfm. C\u00e1c th\u1eed nghi\u1ec7m trong \u1ed1ng nghi\u1ec7m \u0111\u00e3 ch\u1ee9ng minh r\u1eb1ng c\u00e1c h\u1ee3p ch\u1ea5t vanadium c\u00f3 t\u00e1c d\u1ee5ng k\u00edch th\u00edch s\u1ea3n sinh v\u00e0 c\u1ea3i thi\u1ec7n \u0111\u1ed9 nh\u1ea1y insulin, gi\u1ea3m l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng. M\u1ed9t nghi\u00ean c\u1ee9u ri\u00eang bi\u1ec7t tr\u00ean chu\u1ed9t \u0111\u00e3 ch\u1ec9 ra: Coprinus comatus c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 HbA1c (haemoglobin glycosyl h\u00f3a, m\u1ed9t th\u01b0\u1edbc \u0111o l\u00e2u d\u00e0i v\u1ec1 l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u cao) \u1edf chu\u1ed9t ti\u1ec3u \u0111\u01b0\u1eddng, c\u0169ng nh\u01b0 c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng dung n\u1ea1p \u0111\u01b0\u1eddng \u1edf chu\u1ed9t b\u00ecnh th\u01b0\u1eddng (kh\u00f4ng m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng).<\/p>\n\n\n\n

B\u00ean c\u1ea1nh \u0111\u00f3, Polysaccharide t\u1eeb Coprinus Comatus g\u00e2y \u1ee9c ch\u1ebf glycosyl h\u00f3a kh\u00f4ng enzyme c\u00f3 th\u1ec3 h\u1ea1n ch\u1ebf c\u00e1c bi\u1ebfn ch\u1ee9ng ti\u1ec3u \u0111\u01b0\u1eddng, nh\u01b0 b\u1ec7nh l\u00fd m\u1ea1ch m\u00e1u v\u0129 m\u00f4 v\u00e0 b\u1ec7nh l\u00fd vi m\u1ea1ch.<\/p>\n\n\n\n

Comatin, h\u1ee3p ch\u1ea5t ph\u00e2n l\u1eadp t\u1eeb Coprinus Comatus, c\u0169ng cho th\u1ea5y \u0111\u1eb7c t\u00ednh ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng. Th\u00ed nghi\u1ec7m so s\u00e1nh t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft c\u1ee7a comatin v\u1edbi thu\u1ed1c tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng ph\u1ed5 bi\u1ebfn metformin. Comatin l\u00e0m gi\u1ea3m m\u1ee9c glucose trong m\u00e1u nhi\u1ec1u h\u01a1n metformin sau 1, 2, 3 v\u00e0 4 gi\u1edd \u1edf chu\u1ed9t m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng. H\u01a1n n\u1eefa, comatin m\u1ea1nh h\u01a1n metformin l\u00e0m gi\u1ea3m c\u00e1c th\u00f4ng s\u1ed1 chuy\u1ec3n h\u00f3a glyco v\u00e0 chuy\u1ec3n h\u00f3a m\u1ee1 nh\u01b0 \u0111\u01b0\u1eddng huy\u1ebft l\u00fac \u0111\u00f3i, \u0111\u01b0\u1eddng huy\u1ebft sau \u0103n, fructosamine, cholesterol to\u00e0n ph\u1ea7n v\u00e0 triglycerid to\u00e0n ph\u1ea7n.<\/p>\n\n\n\n

Link b\u00e0i b\u00e1o tham kh\u1ea3o:<\/p>\n\n\n\n

The two faces of Coprinus comatus\u2014Functional properties and potential hazards – PMC (nih.gov<\/a>)<\/p>\n\n\n\n

Hypoglycaemic effect of comatin, an antidiabetic substance separated from Coprinus comatus broth, on alloxan-induced-diabetic rats – ScienceDirect<\/p>\n\n\n\n

D16C69428447 (academicjournals.org<\/a>)<\/p>\n\n\n\n

Ban bi\u00ean t\u1eadp OPFE.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

\u0110\u00e1i th\u00e1o \u0111\u01b0\u1eddng hay c\u00f2n g\u1ecdi l\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng, l\u00e0 b\u1ec7nh r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a \u0111\u1eb7c tr\u01b0ng v\u1edbi bi\u1ec3u hi\u1ec7n l\u01b0\u1ee3ng \u0111\u01b0\u1eddng \u1edf trong m\u00e1u lu\u00f4n \u1edf m\u1ee9c cao h\u01a1n so v\u1edbi b\u00ecnh th\u01b0\u1eddng do c\u01a1 th\u1ec3 thi\u1ebfu h\u1ee5t v\u1ec1 ti\u1ebft insulin ho\u1eb7c \u0111\u1ec1 kh\u00e1ng v\u1edbi insulin ho\u1eb7c c\u1ea3 2, d\u1eabn \u0111\u1ebfn r\u1ed1i lo\u1ea1n quan tr\u1ecdng v\u1ec1 chuy\u1ec3n h\u00f3a \u0111\u01b0\u1eddng, \u0111\u1ea1m, m\u1ee1, ch\u1ea5t kho\u00e1ng.<\/p>\n","protected":false},"author":1,"featured_media":3537,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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