{"id":4569,"date":"2026-04-21T10:50:50","date_gmt":"2026-04-21T03:50:50","guid":{"rendered":"https:\/\/opfe.vn\/?p=4569"},"modified":"2026-04-21T11:08:49","modified_gmt":"2026-04-21T04:08:49","slug":"orinmn_eva_vn","status":"publish","type":"post","link":"https:\/\/opfe.vn\/index.php\/2026\/04\/21\/orinmn_eva_vn\/","title":{"rendered":"V\u00ec sao ng\u01b0\u1eddi l\u1edbn tu\u1ed5i v\u00e0 ng\u01b0\u1eddi th\u1eeba c\u00e2n c\u00f3 th\u1ec3 kh\u00f4ng \u0111\u00e1p \u1ee9ng t\u1ed1t v\u1edbi m\u1ed9t s\u1ed1 ti\u1ec1n ch\u1ea5t NAD\u207a?"},"content":{"rendered":"\t\t
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Trong l\u00e0n s\u00f3ng ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe hi\u1ec7n \u0111\u1ea1i, NAD+ \u0111ang n\u1ed5i l\u00ean nh\u01b0 \u201cch\u00eca kh\u00f3a\u201d gi\u00fap duy tr\u00ec n\u0103ng l\u01b0\u1ee3ng t\u1ebf b\u00e0o v\u00e0 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a. Khi n\u1ed3ng \u0111\u1ed9 NAD+ suy gi\u1ea3m theo tu\u1ed5i t\u00e1c v\u00e0 t\u00ecnh tr\u1ea1ng th\u1eeba c\u00e2n, vi\u1ec7c b\u1ed5 sung c\u00e1c ti\u1ec1n ch\u1ea5t nh\u01b0 NMN hay NR ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c quan t\u00e2m nh\u01b0 m\u1ed9t gi\u1ea3i ph\u00e1p h\u1ed7 tr\u1ee3 ph\u1ee5c h\u1ed3i s\u1ee9c kh\u1ecfe t\u1eeb b\u00ean trong. Tuy nhi\u00ean, kh\u1ea3 n\u0103ng \u0111\u00e1p \u1ee9ng v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p n\u00e0y c\u00f3 th\u1ec3 kh\u00e1c nhau t\u00f9y t\u1eebng c\u01a1 \u0111\u1ecba.<\/strong><\/em><\/p>

NAD\u207a \u2013 \u201cCh\u00eca kh\u00f3a n\u0103ng l\u01b0\u1ee3ng\u201d c\u1ee7a t\u1ebf b\u00e0o<\/strong><\/h5>

Trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, NAD\u207a \u0111\u01b0\u1ee3c xem l\u00e0 ph\u00e2n t\u1eed trung t\u00e2m gi\u00fap duy tr\u00ec n\u0103ng l\u01b0\u1ee3ng t\u1ebf b\u00e0o, s\u1eeda ch\u1eefa DNA v\u00e0 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a. Tuy nhi\u00ean, nhi\u1ec1u nghi\u00ean c\u1ee9u cho th\u1ea5y m\u1ee9c NAD\u207a suy gi\u1ea3m theo tu\u1ed5i, g\u00f3p ph\u1ea7n g\u00e2y m\u1ec7t m\u1ecfi, r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a v\u00e0 suy gi\u1ea3m ch\u1ee9c n\u0103ng c\u01a1 th\u1ec3 (Verdin, 2015; Yoshino et al., 2018).<\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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B\u1ed9 \u0111\u00f4i s\u1ea3n ph\u1ea9m cao c\u1ea5p OriNMN+ thu\u1ed9c C\u00f4ng ty OPFE KFT., Hungary<\/strong><\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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V\u00ec sao kh\u00f4ng ph\u1ea3i ai c\u0169ng \u0111\u00e1p \u1ee9ng gi\u1ed1ng nhau?<\/strong><\/h5>

C\u00e1c ti\u1ec1n ch\u1ea5t NAD\u207a nh\u01b0 NMN v\u00e0 NR \u0111\u01b0\u1ee3c k\u1ef3 v\u1ecdng h\u1ed7 tr\u1ee3 ph\u1ee5c h\u1ed3i NAD\u207a, nh\u01b0ng hi\u1ec7u qu\u1ea3 c\u00f3 th\u1ec3 kh\u00e1c nhau gi\u1eefa t\u1eebng ng\u01b0\u1eddi. Nguy\u00ean nh\u00e2n n\u1eb1m \u1edf h\u1ec7 th\u1ed1ng chuy\u1ec3n h\u00f3a: NR c\u1ea7n enzyme NRK1 \u0111\u1ec3 chuy\u1ec3n th\u00e0nh NMN tr\u01b0\u1edbc khi t\u1ea1o NAD\u207a. \u1ede ng\u01b0\u1eddi l\u1edbn tu\u1ed5i ho\u1eb7c th\u1eeba c\u00e2n, enzyme n\u00e0y c\u00f3 th\u1ec3 suy gi\u1ea3m ho\u1ea1t \u0111\u1ed9ng, khi\u1ebfn qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a k\u00e9m hi\u1ec7u qu\u1ea3 h\u01a1n (Ratajczak et al., 2016).<\/p>

Trong khi \u0111\u00f3, NMN n\u1eb1m g\u1ea7n h\u01a1n trong chu\u1ed7i chuy\u1ec3n h\u00f3a, c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng hi\u1ec7u qu\u1ea3 h\u01a1n trong \u0111i\u1ec1u ki\u1ec7n sinh l\u00fd kh\u00f4ng t\u1ed1i \u01b0u (Yoshino et al., 2011).<\/p>

R\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a \u2013 y\u1ebfu t\u1ed1 n\u1ec1n t\u1ea3ng b\u1ecb b\u1ecf qua<\/strong><\/h5>

Suy gi\u1ea3m NAD\u207a kh\u00f4ng ch\u1ec9 li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c m\u00e0 c\u00f2n g\u1eafn li\u1ec1n v\u1edbi vi\u00eam m\u1ea1n t\u00ednh, t\u00edch t\u1ee5 m\u1ee1 v\u00e0 kh\u00e1ng insulin – nh\u1eefng y\u1ebfu t\u1ed1 n\u1ec1n c\u1ee7a h\u1ed9i ch\u1ee9ng chuy\u1ec3n h\u00f3a v\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng type 2 (Canto et al., 2012). \u0110i\u1ec1u n\u00e0y cho th\u1ea5y vi\u1ec7c b\u1ed5 sung NAD\u207a \u0111\u01a1n thu\u1ea7n c\u00f3 th\u1ec3 ch\u01b0a \u0111\u1ee7 n\u1ebfu m\u00f4i tr\u01b0\u1eddng t\u1ebf b\u00e0o ch\u01b0a \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n.<\/p>

L\u00e3o h\u00f3a l\u00e0 m\u1ed9t b\u00e0i to\u00e1n \u0111a c\u01a1 ch\u1ebf<\/strong><\/h5>

Theo c\u00e1c chuy\u00ean gia, l\u00e3o h\u00f3a kh\u00f4ng ch\u1ec9 do thi\u1ebfu NAD\u207a m\u00e0 c\u00f2n li\u00ean quan \u0111\u1ebfn stress oxy h\u00f3a, r\u1ed1i lo\u1ea1n t\u00edn hi\u1ec7u n\u1ed9i b\u00e0o v\u00e0 suy gi\u1ea3m kh\u1ea3 n\u0103ng t\u00e1i t\u1ea1o m\u00f4 (Lopez-Ot\u00edn et al., 2013). V\u00ec v\u1eady, h\u01b0\u1edbng ti\u1ebfp c\u1eadn hi\u1ec7n \u0111\u1ea1i kh\u00f4ng c\u00f2n t\u1eadp trung v\u00e0o m\u1ed9t ho\u1ea1t ch\u1ea5t ri\u00eang l\u1ebb, m\u00e0 c\u1ea7n t\u00e1c \u0111\u1ed9ng \u0111\u1ed3ng th\u1eddi l\u00ean nhi\u1ec1u c\u01a1 ch\u1ebf sinh h\u1ecdc.<\/p>

Xu h\u01b0\u1edbng m\u1edbi: H\u1ed7 tr\u1ee3 to\u00e0n di\u1ec7n t\u1eeb b\u00ean trong<\/strong><\/h5>

C\u00e1c gi\u1ea3i ph\u00e1p ti\u00ean ti\u1ebfn hi\u1ec7n nay h\u01b0\u1edbng \u0111\u1ebfn vi\u1ec7c v\u1eeba h\u1ed7 tr\u1ee3 NAD\u207a, v\u1eeba c\u1ea3i thi\u1ec7n m\u00f4i tr\u01b0\u1eddng n\u1ed9i b\u00e0o, ki\u1ec3m so\u00e1t vi\u00eam v\u00e0 th\u00fac \u0111\u1ea9y kh\u1ea3 n\u0103ng t\u00e1i t\u1ea1o t\u1ef1 nhi\u00ean c\u1ee7a c\u01a1 th\u1ec3, bao g\u1ed3m c\u1ea3 h\u1ec7 t\u1ebf b\u00e0o g\u1ed1c n\u1ed9i sinh (Rando, 2006).<\/p>

Trong b\u1ed1i c\u1ea3nh \u0111\u00f3, OriNMN+ Anti-Aging \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n theo \u0111\u1ecbnh h\u01b0\u1edbng \u0111a c\u01a1 ch\u1ebf, k\u1ebft h\u1ee3p c\u00e1c ho\u1ea1t ch\u1ea5t c\u00f3 c\u00f4ng d\u1ee5ng h\u1ed7 tr\u1ee3 c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng l\u00e3o h\u00f3a da.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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L\u1ef1a ch\u1ecdn \u0111\u00fang kh\u00f4ng ph\u1ea3i l\u00e0 \u201ct\u1ed1t nh\u1ea5t\u201d, m\u00e0 l\u00e0 \u201cph\u00f9 h\u1ee3p nh\u1ea5t\u201d<\/strong><\/h5>

M\u1ed7i c\u01a1 th\u1ec3 l\u00e0 m\u1ed9t h\u1ec7 sinh h\u1ecdc kh\u00e1c nhau. Khi tu\u1ed5i t\u00e1c t\u0103ng ho\u1eb7c xu\u1ea5t hi\u1ec7n r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a, c\u00e1ch c\u01a1 th\u1ec3 ph\u1ea3n \u1ee9ng v\u1edbi c\u00f9ng m\u1ed9t ho\u1ea1t ch\u1ea5t c\u0169ng thay \u0111\u1ed5i. V\u00ec v\u1eady, l\u1ef1a ch\u1ecdn gi\u1ea3i ph\u00e1p ph\u00f9 h\u1ee3p c\u1ea7n d\u1ef1a tr\u00ean t\u00ecnh tr\u1ea1ng sinh l\u00fd c\u00e1 nh\u00e2n, thay v\u00ec t\u00ecm ki\u1ebfm m\u1ed9t \u201cc\u00f4ng th\u1ee9c chung cho t\u1ea5t c\u1ea3\u201d.<\/p>

Ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe hi\u1ec7n \u0111\u1ea1i kh\u00f4ng ch\u1ec9 d\u1eebng l\u1ea1i \u1edf vi\u1ec7c b\u1ed5 sung, m\u00e0 l\u00e0 t\u1ed1i \u01b0u to\u00e0n di\u1ec7n h\u1ec7 th\u1ed1ng b\u00ean trong – t\u1eeb n\u0103ng l\u01b0\u1ee3ng t\u1ebf b\u00e0o, t\u00edn hi\u1ec7u sinh h\u1ecdc \u0111\u1ebfn kh\u1ea3 n\u0103ng t\u00e1i t\u1ea1o l\u00e2u d\u00e0i.<\/p>

T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/h5>

Canto, C., Houtkooper, R. H., Pirinen, E., Youn, D. Y., Oosterveer, M. H., Cen, Y., \u2026 Auwerx, J. (2012). The NAD\u207a precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet\u2013induced obesity. Cell Metabolism, 15(6), 838\u2013847.
Lopez-Ot\u00edn, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194\u20131217.
Rando, T. A. (2006). Stem cells, ageing and the quest for immortality. Nature, 441(7097), 1080\u20131086.
Ratajczak, J., Joffraud, M., Trammell, S. A. J., Ras, R., Canela, N., Boutant, M., \u2026 Canto, C. (2016). NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nature Communications, 7, 13103.
Verdin, E. (2015). NAD\u207a in aging, metabolism, and neurodegeneration. Science, 350(6265), 1208\u20131213.
Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. (2011). Nicotinamide mononucleotide treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism, 14(4), 528\u2013536.
Yoshino, J., Baur, J. A., & Imai, S. (2018). NAD\u207a intermediates: Biology and therapeutic potential. Cell Metabolism, 27(3), 513\u2013528.<\/p>

Ngu\u1ed3n:<\/strong> https:\/\/eva.vn\/tin-tuc-suc-khoe\/vi-sao-nguoi-lon-tuoi-va-nguoi-thua-can-co-the-khong-dap-ung-tot-voi-mot-so-tien-chat-nad-c296a668175.html<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Th\u1ef1c ph\u1ea9m BVSK OPFE OriNMN+ Anti aging
Huy ch\u01b0\u01a1ng v\u00e0ng v\u00ec s\u1ee9c kho\u1ebb c\u1ed9ng \u0111\u1ed3ng n\u0103m 2025<\/strong><\/em><\/p>

S\u1ea3n ph\u1ea9m c\u1ee7a Hungary
S\u1ea3n xu\u1ea5t t\u1ea1i: C\u00f4ng ty Novotic Kft.
\u0110\u1ecba ch\u1ec9 c\u00f4ng ty: 6728 Szeged, B\u00e1nk B\u00e1n u. 67. Hungary
Th\u01b0\u01a1ng nh\u00e2n nh\u1eadp kh\u1ea9u v\u00e0 ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m:
C\u00f4ng ty TNHH OPFE Vi\u1ec7t Nam
\u0110\u1ecba ch\u1ec9: 315 Ph\u1ed1 V\u1ecdng, Ph\u01b0\u1eddng T\u01b0\u01a1ng Mai, Th\u00e0nh ph\u1ed1 H\u00e0 N\u1ed9i, Vi\u1ec7t Nam
S\u1ed1 \u0110KSP: 5983\/2024\/\u0110KSP
S\u1ed1 gi\u1ea5y ph\u00e9p x\u00e1c nh\u1eadn n\u1ed9i dung qu\u1ea3ng c\u00e1o: 1999\/2024\/XNQC-ATTP<\/p>

Th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe\u00a0OPFE OriNMN+ Anti aging<\/a>\u00a0l\u00e0 s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1ea1i Hungary (Made in EU), ph\u1ed1i h\u1ee3p c\u00e1c ti\u1ec1n ch\u1ea5t NAD\u207a nh\u01b0 NMN v\u00e0 NR c\u00f9ng v\u1edbi c\u00e1c h\u1ee3p ch\u1ea5t sinh h\u1ecdc nh\u00f3m polyphenol (resveratrol, fisetin, apigenin). S\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n nh\u1eb1m h\u1ed7 tr\u1ee3 c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng l\u00e3o ho\u00e1 da. S\u1ea3n ph\u1ea9m \u0111\u00e3 vinh d\u1ef1 nh\u1eadn gi\u1ea3i th\u01b0\u1edfng\u00a0\u201cHuy ch\u01b0\u01a1ng v\u00e0ng v\u00ec s\u1ee9c kh\u1ecfe c\u1ed9ng \u0111\u1ed3ng n\u0103m 2025\u201d\u00a0do Hi\u1ec7p h\u1ed9i Th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng Vi\u1ec7t Nam trao t\u1eb7ng ng\u00e0y 13\/01\/2025.<\/strong><\/p><\/blockquote>

Th\u00f4ng tin chi ti\u1ebft m\u1eddi tham kh\u1ea3o t\u1ea1i website:\u00a0https:\/\/opfe.vn<\/a><\/p>

Th\u1ef1c ph\u1ea9m n\u00e0y kh\u00f4ng ph\u1ea3i l\u00e0 thu\u1ed1c v\u00e0 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng thay th\u1ebf thu\u1ed1c ch\u1eefa b\u1ec7nh.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Trong l\u00e0n s\u00f3ng ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe hi\u1ec7n \u0111\u1ea1i, NAD+ \u0111ang n\u1ed5i l\u00ean nh\u01b0 \u201cch\u00eca kh\u00f3a\u201d gi\u00fap duy tr\u00ec n\u0103ng l\u01b0\u1ee3ng t\u1ebf b\u00e0o v\u00e0 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a. Khi n\u1ed3ng \u0111\u1ed9 NAD+ suy gi\u1ea3m theo tu\u1ed5i t\u00e1c v\u00e0 t\u00ecnh tr\u1ea1ng th\u1eeba c\u00e2n, vi\u1ec7c b\u1ed5 sung c\u00e1c ti\u1ec1n ch\u1ea5t nh\u01b0 NMN hay NR ng\u00e0y […]<\/p>\n","protected":false},"author":1,"featured_media":4570,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[41,42],"tags":[],"class_list":["post-4569","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-suc-khoe","category-tin-tuc"],"aioseo_notices":[{"message":"The permalink for this post just changed! 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